abstract：BACKGROUND:Recent data have shown that HTLV-1 is prevalent among HIV positive patients in Mozambique, although the impact of HTLV-1 infection on HIV disease progression remains controversial. Our aim was to determine the phenotypic profile of T lymphocytes subsets among Mozambican patients co-infected by HIV and HTLV-1...

journal_title：BMC infectious diseases

authors： Gudo ES,Bhatt NB,Bila DR,Abreu CM,Tanuri A,Savino W,Silva-Barbosa SD,Jani IV

更新日期：2009-12-22 00:00:00

abstract：BACKGROUND:Chikungunya fever is an emerging arboviral disease characterized by an algo-eruptive syndrome, inflammatory polyarthralgias, or tenosynovitis that can last for months to years. Up to now, the pathophysiology of the chronic stage is poorly understood. CASE PRESENTATION:We report the first case of CHIKV infec...

journal_title：BMC infectious diseases

authors： Malvy D,Ezzedine K,Mamani-Matsuda M,Autran B,Tolou H,Receveur MC,Pistone T,Rambert J,Moynet D,Mossalayi D

更新日期：2009-12-10 00:00:00

abstract：BACKGROUND:Syndromic surveillance is increasingly being evaluated for its potential for early warning of increased disease activity in the population. However, interpretation is hampered by the difficulty of attributing a causative pathogen. We described the temporal relationship between laboratory counts of influenza ...

journal_title：BMC infectious diseases

authors： Schindeler SK,Muscatello DJ,Ferson MJ,Rogers KD,Grant P,Churches T

更新日期：2009-11-29 00:00:00

abstract：BACKGROUND:Chemokines have been reported to play an important role in granulomatous inflammation during Schistosoma mansoni infection. However there is less information on their role in Schistosoma haematobium infection, or on the effect of concurrent HIV-1 infection, as a potential modifying influence. METHODS:To det...

journal_title：BMC infectious diseases

authors： Zinyama-Gutsire R,Gomo E,Kallestrup P,Erikstrup C,Ullum H,Butterworth AE,Munyati S,Mduluza T

更新日期：2009-10-23 00:00:00

abstract：BACKGROUND:The ocular manifestations of HIV may lead to visual impairment or blindness. In India, patients typically initiate antiretroviral treatment (ART) with low CD4 cell counts when the risk of ocular complications may be high. The objective of this study was to determine the prevalence and types of HIV-associated...

journal_title：BMC infectious diseases

authors： Pathai S,Deshpande A,Gilbert C,Lawn SD

更新日期：2009-09-23 00:00:00

abstract：BACKGROUND:HIV infection has been modifying both the epidemiology and outcome of parasitic infections. Hence, this study was undertaken to determine the prevalence of intestinal parasitic infection among people with and without HIV infection and its association with diarrhea and CD4 T-cell count. METHODS:A cross-secti...

journal_title：BMC infectious diseases

authors： Assefa S,Erko B,Medhin G,Assefa Z,Shimelis T

更新日期：2009-09-18 00:00:00

abstract：BACKGROUND:DNA fingerprinting of Mycobacterium tuberculosis isolates offers better opportunities to study links between tuberculosis (TB) cases and can highlight relevant issues in urban TB control in low-endemic countries. METHODS:A medium-sized molecular cluster of TB cases with identical DNA fingerprints was used f...

journal_title：BMC infectious diseases

authors： de Vries G,van Hest RA,Burdo CC,van Soolingen D,Richardus JH

更新日期：2009-09-08 00:00:00

abstract：BACKGROUND:There is little knowledge regarding the prevalence and nature of renal impairment in African populations initiating antiretroviral treatment, nor evidence to inform the most cost effective methods of screening for renal impairment. With the increasing availability of the potentially nephrotixic drug, tenofov...

journal_title：BMC infectious diseases

authors： Franey C,Knott D,Barnighausen T,Dedicoat M,Adam A,Lessells RJ,Newell ML,Cooke GS

更新日期：2009-08-28 00:00:00

abstract：BACKGROUND:In general, the Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) population has begun to experience the benefits of highly active antiretroviral therapy (HAART); unfortunately, these benefits have not extended equally to Blacks in the United States, possibly due to differences in pa...

journal_title：BMC infectious diseases

authors： Oramasionwu CU,Hunter JM,Skinner J,Ryan L,Lawson KA,Brown CM,Makos BR,Frei CR

更新日期：2009-08-11 00:00:00

abstract：BACKGROUND:The incidence of community-associated methicillin-resistant Staphylococcus aureus (MRSA) has risen dramatically in the U.S., particularly among children. Although Streptococcus pneumoniae colonization has been inversely associated with S. aureus colonization in unvaccinated children, this and other risk fact...

journal_title：BMC infectious diseases

authors： Lee GM,Huang SS,Rifas-Shiman SL,Hinrichsen VL,Pelton SI,Kleinman K,Hanage WP,Lipsitch M,McAdam AJ,Finkelstein JA

更新日期：2009-07-11 00:00:00

abstract：BACKGROUND:The purpose of this study was to further characterize the immune response to Mycobacterium tuberculosis (Mtb) antigens, in order to provide new insight into host-pathogen interactions in tuberculosis (TB), and to offer tools for a more accurate diagnosis of the different stages of TB. METHODS:T-cell respons...

journal_title：BMC infectious diseases

authors： Sargentini V,Mariotti S,Carrara S,Gagliardi MC,Teloni R,Goletti D,Nisini R

更新日期：2009-06-23 00:00:00

abstract：BACKGROUND:Low density Plasmodium falciparum infections, below the microscopic detection limit, may play an important role in maintaining malaria transmission in low endemic areas as well as contribute to the maintenance of acquired immunity. Little is known about factors influencing the occurrence of sub-microscopic p...

journal_title：BMC infectious diseases

authors： Shekalaghe S,Alifrangis M,Mwanziva C,Enevold A,Mwakalinga S,Mkali H,Kavishe R,Manjurano A,Sauerwein R,Drakeley C,Bousema T

更新日期：2009-05-21 00:00:00

abstract：BACKGROUND:In patients with chronic respiratory disease, Pneumocystis jirovecii (P. jirovecii) colonization is observed, and may influence disease progression and systemic inflammation. Pneumocystis pneumonia causes interstitial changes, so making a diagnosis of PCP in patients who have interstitial pneumonia (IP) with...

journal_title：BMC infectious diseases

authors： Shimizu Y,Sunaga N,Dobashi K,Fueki M,Fueki N,Makino S,Mori M

更新日期：2009-04-22 00:00:00

abstract：BACKGROUND:The usefulness of procalcitonin (PCT) measurement in critically ill medical patients with suspected nosocomial infection is unclear. The aim of the study was to assess PCT value for the early diagnosis of bacterial nosocomial infection in selected critically ill patients. METHODS:An observational cohort stu...

journal_title：BMC infectious diseases

authors： Charles PE,Kus E,Aho S,Prin S,Doise JM,Olsson NO,Blettery B,Quenot JP

更新日期：2009-04-22 00:00:00

abstract：BACKGROUND:Haemophilus influenzae type b (Hib) vaccination led to a significant decrease in invasive bacterial infections in children. The aim of this study was to assess a potential shift to more non-type b invasive infections in a population with high Hib vaccination coverage and to compare the burden of suffering be...

journal_title：BMC infectious diseases

authors： Kalies H,Siedler A,Gröndahl B,Grote V,Milde-Busch A,von Kries R

更新日期：2009-04-20 00:00:00

abstract：BACKGROUND:Clinical outcomes of spontaneous bacterial peritonitis (SBP) due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species (ESBL-EK) have not been adequately investigated. METHODS:We conducted a retrospective matched case-control study to evaluate the outcomes of SBP due to ESBL-...

journal_title：BMC infectious diseases

authors： Song KH,Jeon JH,Park WB,Park SW,Kim HB,Oh MD,Lee HS,Kim NJ,Choe KW

更新日期：2009-04-12 00:00:00

abstract：BACKGROUND:Little is known about the prevalence of HIV or HCV in injecting drug users (IDUs) in Serbia and Montenegro. We measured prevalence of antibodies to HIV (anti-HIV) and hepatitis C virus (anti-HCV), and risk factors for anti-HCV, in community-recruited IDUs in Belgrade and Podgorica, and determined the perform...

journal_title：BMC infectious diseases

authors： Judd A,Rhodes T,Johnston LG,Platt L,Andjelkovic V,Simić D,Mugosa B,Simić M,Zerjav S,Parry RP,Parry JV

更新日期：2009-02-09 00:00:00

abstract：BACKGROUND:The identification and differentiation of strains of Mycobacterium tuberculosis by DNA fingerprinting has provided a better understanding of the epidemiology and tracing the transmission of tuberculosis. We set out to determine if there was a relationship between the risk of belonging to a group of tuberculo...

journal_title：BMC infectious diseases

authors： Asiimwe BB,Joloba ML,Ghebremichael S,Koivula T,Kateete DP,Katabazi FA,Pennhag A,Petersson R,Kallenius G

更新日期：2009-02-05 00:00:00

abstract：BACKGROUND:Our aim was to determine the efficacy of a trivalent inactivated split virus influenza vaccine (TIV) against culture-confirmed influenza A and/or B in adults 18 to 64 years of age during the 2005/2006 season in the Czech Republic. METHODS:6203 subjects were randomized to receive TIV (N = 4137) or placebo (N...

journal_title：BMC infectious diseases

authors： Beran J,Wertzova V,Honegr K,Kaliskova E,Havlickova M,Havlik J,Jirincova H,Van Belle P,Jain V,Innis B,Devaster JM

更新日期：2009-01-17 00:00:00

abstract：BACKGROUND:Blood stream infections (BSI) are life-threatening infections in intensive care units (ICU), and prognosis is highly dependent on early detection. Procalcitonin levels have been shown to accurately and quickly distinguish between BSI and noninfectious inflammatory states in critically ill patients. It is, ho...

journal_title：BMC infectious diseases

authors： Charles PE,Ladoire S,Snauwaert A,Prin S,Aho S,Pechinot A,Olsson NO,Blettery B,Doise JM,Quenot JP

更新日期：2008-12-02 00:00:00

abstract：BACKGROUND:It is unclear whether appropriate empiric antimicrobial therapy improves outcomes in patients with bacteremia due to Escherichia coli or Klebsiella. The objective of this study is to assess the impact of appropriate empiric antimicrobial therapy on in-hospital mortality and post-infection length of stay in p...

journal_title：BMC infectious diseases

authors： Thom KA,Schweizer ML,Osih RB,McGregor JC,Furuno JP,Perencevich EN,Harris AD

更新日期：2008-09-15 00:00:00

abstract：BACKGROUND:Relapse of tuberculosis (TB) may develop as the result of reactivation of the endogenous primary infection, or as a result of a exogenous reinfection. This survey evaluated the rate of reactivation versus recent transmission among Iranian and Afghan relapse cases. METHODS:The sputum specimens were digested,...

journal_title：BMC infectious diseases

authors： Farnia P,Masjedi MR,Varahram M,Mirsaeidi M,Ahmadi M,Khazampour M,Tabarsi P,Baghei P,Marjane M,Bahadori M,Zarifi AZ,Velayati AA

更新日期：2008-08-06 00:00:00

abstract：BACKGROUND:In developing countries rotavirus is the leading cause of severe diarrhoea and diarrhoeal deaths in children under 5. Vaccination could greatly alleviate that burden, but in Mexico as in most low- and middle-income countries the decision to add rotavirus vaccine to the national immunisation program will depe...

journal_title：BMC infectious diseases

authors： Valencia-Mendoza A,Bertozzi SM,Gutierrez JP,Itzler R

更新日期：2008-07-29 00:00:00

abstract：BACKGROUND:In Tashkent (Uzbekistan), TB treatment is provided in accordance with the DOTS strategy. Of 1087 pulmonary TB patients started on treatment in 2005, 228 (21%) defaulted. This study investigates who the defaulters in Tashkent are, when they default and why they default. METHODS:We reviewed the records of 126...

journal_title：BMC infectious diseases

authors： Hasker E,Khodjikhanov M,Usarova S,Asamidinov U,Yuldashova U,van der Werf MJ,Uzakova G,Veen J

更新日期：2008-07-22 00:00:00

abstract：BACKGROUND:How HIV-1 enter into the eyes remains obscure. We postulated that HIV-1 Tat protein can alter the expression of specific tight-junction proteins and disturb the blood retinal barrier, and contributes to HIV trafficking into the eyes. This study is to determine the effects of HIV-1 Tat proteins on the barrier...

journal_title：BMC infectious diseases

authors： Bai L,Zhang Z,Zhang H,Li X,Yu Q,Lin H,Yang W

更新日期：2008-06-06 00:00:00

abstract：BACKGROUND:Escherichia coli infections are frequent in ICU patients. The increased resistance to fluoroquinolones and amoxicillin/clavulanate of this pathogen mandates the prescription of broad-spectrum antibiotics such as piperacillin/tazobactam (PIP-TAZ) or third generation cephalosporins (3GC). METHODS:To assess in...

journal_title：BMC infectious diseases

authors： Meybeck A,Ricard JD,Barnaud G,Eveillard M,Chevrel G,Mounier R,Dreyfuss D

更新日期：2008-05-17 00:00:00

abstract：BACKGROUND:Although breast-feeding accounts for 15-20% of mother-to-child transmission (MTCT) of HIV, it is not prohibited in some developing countries because of the higher mortality associated with not breast-feeding. We assessed the potential impact, on HIV infection and infant mortality, of a recommendation for sho...

journal_title：BMC infectious diseases

authors： Atashili J,Kalilani L,Seksaria V,Sickbert-Bennett EE

更新日期：2008-05-16 00:00:00

abstract：BACKGROUND:Australia is developing a chlamydia screening program. This study aimed to determine the attitudes of young women to the introduction of chlamydia screening in Australian General Practice. METHODS:In-depth face-to-face interviews with 24 young women from across Victoria, Australia, attending a randomly sele...

journal_title：BMC infectious diseases

authors： Pavlin NL,Parker R,Fairley CK,Gunn JM,Hocking J

更新日期：2008-05-09 00:00:00

abstract：BACKGROUND:A novel Ehrlichia, closely related to Ehrlichia ruminantium, was recently discovered from Panola Mountain State Park, GA, USA. We conducted a study to determine if this agent was recently introduced into the United States. METHODS:We developed a sensitive PCR assay based on the conserved gltA (citrate synth...

journal_title：BMC infectious diseases

authors： Loftis AD,Mixson TR,Stromdahl EY,Yabsley MJ,Garrison LE,Williamson PC,Fitak RR,Fuerst PA,Kelly DJ,Blount KW

更新日期：2008-04-23 00:00:00

abstract：BACKGROUND:In some populations, complete shifts in the genotype of the strain of measles circulating in the population have been observed, with given genotypes being replaced by new genotypes. Studies have postulated that such shifts may be attributable to differences between the fitness of the new and the old genotype...

journal_title：BMC infectious diseases

authors： Nojiri S,Vynnycky E,Gay N

更新日期：2008-04-11 00:00:00

abstract：BACKGROUND:Hepatitis B (HBV) and C (HCV) infections are a serious global and national public health problem. Earlier studies have reported increasing rates of hepatitis infection in Pakistan, particularly in rural areas. Pakistan has no active surveillance program to monitor trends of these infections. The objective of...

journal_title：BMC infectious diseases

authors： Mujeeb SA,Pearce MS

更新日期：2008-04-10 00:00:00

abstract：BACKGROUND:There is little information on nasopharyngeal (NP) flora or bacteremia in HIV-infected children. Our aim was to describe the organisms and antimicrobial resistance patterns in children enrolled in a prospective study comparing daily and three times weekly trimethoprim-sulfamethoxazole (TMP-SMX) and isoniazid...

journal_title：BMC infectious diseases

authors： Cotton MF,Wasserman E,Smit J,Whitelaw A,Zar HJ

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Active tuberculosis (TB) is common among HIV-infected persons living in tuberculosis endemic countries, and screening for tuberculosis (TB) is recommended routinely. We sought to determine the role of chest x-ray and sputum culture in the decision to treat for presumptive TB using active case finding in a la...

journal_title：BMC infectious diseases

authors： Bakari M,Arbeit RD,Mtei L,Lyimo J,Waddell R,Matee M,Cole BF,Tvaroha S,Horsburgh CR,Soini H,Pallangyo K,von Reyn CF

更新日期：2008-03-06 00:00:00

abstract：BACKGROUND:Nonencapsulated and nontypeable Haemophilus influenzae (NTHi) is a major cause of human respiratory tract infections. Some strains of NTHi can cause invasive diseases such as septicemia and meningitis, even if H. influenzae is not generally considered to be an intracellular pathogen. There have been very few...

journal_title：BMC infectious diseases

authors： Sekiya Y,Eguchi M,Nakamura M,Ubukata K,Omura S,Matsui H

更新日期：2008-02-07 00:00:00

abstract：BACKGROUND:Although resistance to isoniazid (INH) is the most common form of drug resistance seen among Mycobacterium tuberculosis isolates, there have been few studies on the efficacy and optimal duration of treatment for patients with INH-resistant tuberculosis (TB). METHODS:We evaluated retrospectively the treatmen...

journal_title：BMC infectious diseases

authors： Kim YH,Suh GY,Chung MP,Kim H,Kwon OJ,Lim SY,Lim SY,Koh WJ

更新日期：2008-01-23 00:00:00

abstract：BACKGROUND:There is paucity of data on seasonal variation in pulmonary tuberculosis (TB) in developing countries contrary to recognized seasonality in the TB notification in western societies. This study examined the seasonal pattern in TB diagnosis among migrant workers from developing countries entering Kuwait. METH...

journal_title：BMC infectious diseases

authors： Akhtar S,Mohammad HG

更新日期：2008-01-07 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) infection is a significant public health problem that may lead to chronic liver disease, cirrhosis, and hepatocellular carcinoma (HCC). Approximately 30% of the world's population has been infected with HBV and approximately 350 million (5-6%) are persistent carriers. More than 120 mi...

journal_title：BMC infectious diseases

authors： Zeng Z,Guan L,An P,Sun S,O'Brien SJ,Winkler CA,HBV study consortium.

更新日期：2008-01-02 00:00:00

abstract：BACKGROUND:Mycobacterium tuberculosis can enter into a dormant state which has resulted in one third of the world's population being infected with latent tuberculosis making the study of latency and reactivation of utmost importance. M. tuberculosis encodes five resuscitation promoting factors (Rpfs) that bear strong s...

journal_title：BMC infectious diseases

authors： Biketov S,Potapov V,Ganina E,Downing K,Kana BD,Kaprelyants A

更新日期：2007-12-17 00:00:00

abstract：BACKGROUND:Procalcitonin (PCT) is an inflammatory marker that has been used as indicator of severe bacterial infection. We evaluated the concentrations of PCT as a marker for systemic infection compared to C-reactive protein (CRP) in patients neutropenic febrile. METHODS:52 adult patients were enrolled in the study. B...

journal_title：BMC infectious diseases

authors： Massaro KS,Costa SF,Leone C,Chamone DA

更新日期：2007-11-22 00:00:00

abstract：BACKGROUND:High blood levels of soluble urokinase Plasminogen Activator Receptor (suPAR) are associated with poor outcomes in human immunodeficiency-1 (HIV-1) infected individuals. Research on the clinical value of suPAR in HIV-1 infection led to the development of the suPARnostic(R) assay for commercial use in 2006. T...

journal_title：BMC infectious diseases

authors： Schneider UV,Nielsen RL,Pedersen C,Eugen-Olsen J

更新日期：2007-11-16 00:00:00